Freebase · USP grade
PurNic™ Nicotine
Our core USP-grade freebase, assayed at 99.7–100% purity and shipped in nitrogen-packed, foil-sealed HDPE.
- Strengths
- 100 / 250 / 1000
- Bases
- VG / 50-50 / PG
- Volumes
- 1 / 2.5 / 55 gal
ISO 9001:2015 · cGMP · US MANUFACTURED
Every form of nicotine, held to one specification.
Tobacco-derived and tobacco-free synthetic. Freebase and salt, 100 to 1000 mg/mL, in Vegetable Glycerin, Propylene Glycol or 50/50. Polacrilex and bitartrate powders for pouches and lozenges. All of it blended, bottled and batch-tested by HPLC and GCMS in our ISO 8 cleanroom in Thousand Oaks, California.
- 99.7–100%Assayed purity
- ISO 8Cleanroom
- 100%Batches tested
- Since 2014US manufacturer
Shipped since 2014
We ship by the bottle, drum, and tote.
Every gallon we have shipped since 2014, blended, filled and batch-tested in our own California facility, counted from our own order records and net of returns.
-
950,101gallons
Nicotine
Freebase, salt, synthetic, every concentration
-
2,600,299gallons
Vegetable glycerin
USP grade, as diluent and as carrier
-
620,015gallons
Propylene glycol
USP grade, as diluent and as carrier
-
260,012gallons
Flavor concentrate
FEMA/GRAS, every house we have carried
Updated daily from our order records. Last counted
Certified and registered
Verifiable compliance, on the record.
Every registration, certificate and license number we hold is published here. Certificates of analysis are available for every batch on request.
- ISO 9001:2015 certified
- C0427497-IS1
- cGMP certified
- 113 06.02.055 09691
- FDA establishment identifier
- 3013538145
- Tobacco Product Master Files
- Completed
- Environmental assessment
- Completed
- Tobacco manufacturers license
- 090300744
- Tobacco retailers license
- 246926080
- Tobacco distributors license
- 090008374
- EPA identification
- 000286898
- Years in business
- 12 · since 2014
Talk to us
Need a custom nicotine formula?
Tell us what you are formulating and we will come back with specifications, lead times and pricing.
- USP grade nicotine
- 99.7–100% assayed purity
- ISO 8 cleanroom
- HPLC and GCMS verified
- Certificate of analysis per lot
- cGMP documented
- Tobacco Master Files on file
- FEI 3013538145
- Manufactured in Thousand Oaks, California
The range
Freebase, salt, synthetic and powder — six lines from one cleanroom.
Most suppliers carry one or two of these. Nicotine River blends, bottles and batch-tests all six by HPLC or GCMS in our ISO 8 cleanroom in Thousand Oaks, so a single specification and a single certificate of analysis cover whatever form your formulation calls for.
Swipe
Nicotine salts · Hit & Smooth
PurNic™ Salt Nicotine
Nicotine salt in two profiles from the same cleanroom: Hit for a sharper throat feel, Smooth for a softer one.
- Strengths
- 100 / 250
- Bases
- VG / 50-50 / PG
- Profiles
- Hit / Smooth
Powder · Oral formats
PurNic™ Powder
Two soluble powders used in nicotine replacement therapy, for pouches, lozenges and ingestibles, not e-liquid.
- Grades
- Polacrilex / Bitartrate
- Assay
- 200 / 340 mg/g
- Amounts
- 1 / 50 / 100 / 250 kg
Tobacco-free · Freebase
SyNic Nicotine
Synthetic (S)-nicotine, typically 99.9% pure, from no part of the tobacco plant. A direct replacement for leaf nicotine.
- Strengths
- 100 / 250 / 1000
- Purity
- Typically 99.9%
- Conforms to
- USP and EP
Tobacco-free · Salt
SyNic Salt Nicotine
The same synthetic (S)-nicotine in Hit and Smooth salt profiles, for markets that require a tobacco-free declaration.
- Strengths
- 100 / 250
- Profiles
- Hit / Smooth
- Bases
- VG / PG
Alternative · Patent pending
Nixodine-S
(S)-6-methylnicotine, blended in our Thousand Oaks cleanroom and offered in liquid, salt and powder forms.
- Forms
- Liquid / Salt / Powder
- Strengths
- 100 / 250 / 1000
- Powder grades
- Polacrilex / Bitartrate
Swipe
OUR ORIGINS
QUALITY BEGINS AT OUR ORIGIN.
Nicotine River is one of the world's largest cGMP compliant suppliers of USP Grade Nicotine and FEMA/GRAS Flavors. Since 2014 we have served businesses large and small, from a single gallon to a 55 gallon drum, with products that break the boundaries of quality, safety and innovation in this industry. Every batch we make is tested before it ships.
MADE IN USA
PROUDLY MANUFACTURED IN THE USA
Our USP Grade Nicotine is made at our FDA registered facility in Thousand Oaks, California, where we employ hard-working Americans. Blending, filling and batch testing all happen in one 45,000 square foot building, covered by our FDA establishment registration and California's tobacco manufacturing and distribution licenses.
PRODUCT SAFETY
OUR TOP PRIORITY IS PRODUCT SAFETY.
Every batch is assayed in our own laboratory before release, by HPLC and GCMS, for purity, identity, residual solvents, pH and specific gravity. That laboratory is accredited to ISO/IEC 17025, and our quality system is built to 21 CFR Part 211, the FDA's rules for finished pharmaceuticals. Nothing ships on a supplier certificate alone.
SUSTAINABILITY
NICOTINE, & OUR PLANET. THEY’RE ONE AND THE SAME.
Nicotine River is proving that nicotine production can be clean and sustainable. Manufacturing releases no toxic or hazardous emissions and discharges nothing onto land or into water. Waste oils, solvents and chemicals are recycled or disposed of through a contracted service, and we keep hazardous stock to a minimum.
Making e-liquid?
Freebase or salt, leaf-derived or synthetic, 100 to 1000 mg/mL, in vegetable glycerin, propylene glycol or 50/50 — from a single gallon to a 55 gallon drum.
Compare liquid nicotineMaking pouches or lozenges?
Nicotine polacrilex USP 20% and nicotine bitartrate dihydrate 34%, both soluble powders commonly used in nicotine replacement therapy, in 1 to 250 kilogram amounts.
See the powdersNeed a tobacco-free declaration?
SyNic synthetic (S)-nicotine is obtained from no part of the tobacco plant and conforms to USP and EP specifications, so it drops into an existing formulation unchanged.
See SyNic